| Common Name | IMMU-130, hMN-14-SN-38, hMN-14-SN-38 ADC, hMN14-CL-SN-38, hMN14-SN-38 |
|---|---|
| Synonyms | CEACAM-5;CD66e;CEA;Meconium antigen 100 |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Humanized |
| IgG type | IgG1 |
| Reactivity | Human |
| Target | |
| Uniprot ID | P06731 |
| Description | Anti-CEACAM5 (labetuzumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
| Conjugate | Unconjugated |
Anti-CEACAM5 (labetuzumab biosimilar) mAb
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Product Data
图片
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CEACAM5, His tagged protein PME100071 can bind Anti-CEACAM5 Neutralizing antibody(BME100035) in a linear range of 2.56-320 ng/ml.
Figure 2. Flow cytometry analysis with Anti-CEACAM5 (labetuzumab ) on Expi293 cells transfected with human CEACAM5 (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of anti-human CEACAM5 mAb(BME100035).
(A) A clear peak shift of BME100035 was seen compared to the control when incubated with CEACAM5-expressing MKN45 cells, indicating strong binding of BME100035 to CEACAM5. Antibodies were incubated at 2 μg/mL.
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