Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb

Name: Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb - 专注肿瘤免疫
SKU: DMC100120

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

SKU: DMC100120 Category: Monoclonal Antibodies

Datasheet

MSDS

Product Data

Clone ID	1B5
Target	CEACAM5
Synonyms	CEACAM-5;CD66e;CEA;Meconium antigen 100
Host Species	Rabbit
Description	Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb
Delivery	In Stock
Uniprot ID	P06731
IgG type	Rabbit/Human Fc chimeric IgG1
Clonality	Monoclonal
Reactivity	Human
Applications	WB
Recommended Dilutions	WB 1:1000
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Usage	Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement.
Conjugate	Unconjugated

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Figure 1.Anti-CEACAM5 antibody (SKU# DMC100120) at 1/1000 dilution

Lane : HT55, whole cell lysate

Secondary : Goat Anti-Rabbit IgG H&L (HRP) at 1/5000 dilution

Predicted band size: 76kDa
Observed band size: 50，250 kDa

Figure 2. Flow cytometry analysis of antigen binding of anti-human CEACAM5 mAb(DMC100120).
(A) DMC100120 does not bind to CHO-S cells that do not express CEACAM5.
(B) A clear peak shift of DMC100120 was seen compared to the control when incubated with CEACAM5-expressing MKN45 cells, indicating strong binding of DMC100120 to CEACAM5. Antibodies were incubated at 5 μg/mL.

Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb

Product Data

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