Anti-CD79B(polatuzumab biosimilar) mAb

Name: Anti-CD79B(polatuzumab biosimilar) mAb - 专注肿瘤免疫
SKU: BME100171
Price: 160.00 CNY
Availability: InStock

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

SKU: BME100171 Category: Biosimilar reference antibodies

Datasheet

MSDS

Product Data

Common Name	RO5541077、RG-7596
Synonyms	B29;IGB
Applications	ELISA, Flow Cyt
Recommended Dilutions	ELISA 1:5000-10000, Flow Cyt 1:100
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Host Species	Humanized
IgG type	IgG1
Reactivity	Human
Target	CD79B
Uniprot ID	P40259
Description	Anti-CD79B(polatuzumab biosimilar) mAb
Delivery	In Stock
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Usage	Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement.
Conjugate	Unconjugated

图片

BME100171-CD79b-Fig.1-FC-1.png
Figure 1. Flow cytometry analysis with 15μg/mL Anti-CD79B(polatuzumab biosimilar) mAb (BME100171) on Expi293 cells transfected with Human CD79B protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
BME100171-CD79B-Fig.2-Elisa-1.png
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CD79B Protein, hFc Tag(PME101089) can bind Anti-CD79B(polatuzumab biosimilar) mAb(BME100171) in a linear range of 0.64–16 ng/mL. In order to specifically detect BME100171, mouse anti-human Fab-specific antibody was used as detection antibody.

Figure 3. Flow cytometry analysis of antigen binding of anti-human CD79B mAb(BME100171).
(A) BME100171 does not bind to 293T cells that do not express CD79B.
(B) A clear peak shift of BME100171 was seen compared to the control when incubated with CD79B-expressing Raji cells, indicating strong binding of BME100171 to CD79B. Antibodies were incubated at 5 μg/mL.

Anti-CD79B(polatuzumab biosimilar) mAb

Product Data

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