Anti-CD74 antibody(DMC674), IgG1 Chimeric mAb

Name: Anti-CD74 antibody(DMC674), IgG1 Chimeric mAb - 专注肿瘤免疫
SKU: DMC100674

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

SKU: DMC100674 Category: Monoclonal Antibodies

Datasheet

MSDS

Product Data

Clone ID	DMC674
Target	CD74
Synonyms	DHLAG; HLADG; Ia-GAMMA; II; p33
Host Species	Rabbit
Description	Anti-CD74 antibody(DMC674); IgG1 Chimeric mAb
Delivery	In Stock
Uniprot ID	P04233
IgG type	Rabbit/Human Fc chimeric IgG1
Clonality	Monoclonal
Reactivity	Human
Applications	Flow Cyt
Recommended Dilutions	Flow Cyt 1:100
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which; when bound to the encoded protein; initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq; Aug 2011]
Usage	Research use only
Conjugate	Unconjugated
DIMA Disclaimer	All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement.

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DMC100674-CD74-Fig.1-FC-1.jpg
Figure 1. Flow cytometry analysis with Anti-CD74(DMC674) on Expi293 cells transfected with human CD74(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Figure 2. Flow cytometry analysis of antigen binding of anti-human CD74 mAb(DMC100674).

(A) DMC100674 does not bind to 293T cells that do not express CD74.
(B) A clear peak shift of DMC100674 was seen compared to the control when incubated with CD74-expressing Raji cells, indicating strong binding of DMC100674 to CD74. Antibodies were incubated at 5 μg/mL.

Anti-CD74 antibody(DMC674), IgG1 Chimeric mAb

Product Data

图片

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