| Clone ID | 1G2 |
|---|---|
| Target | |
| Synonyms | CD3e;T3E |
| Host Species | Rabbit |
| Description | Anti-CD3E antibody(1G2), IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P07766 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1/100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
Anti-CD3E antibody(1G2), IgG1 Chimeric mAb
Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00
Product Data
图片
Figure 1. Flow cytometry analysis with 1μg/mL Anti-CD3E (1G2) mAb on Jurkat cells.
Figure 2. Flow cytometry analysis of antigen binding of anti-human CD3E mAb(DMC101085).
(A) DMC101085 does not bind to 293T cells that do not express CD3E.
(B) A clear peak shift of DMC101085 was seen compared to the control when incubated with CD3E-expressing Jurkat cells, indicating strong binding of DMC101085 to CD3E. Antibodies were incubated at 5 μg/mL.
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