| Common Name | JNJ-61610588 |
|---|---|
| Synonyms | VISTA;VSIR;Sisp-1;C10orf54;DD1alpha;Dies1;GI24;PD-1H;PP2135 |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Homo sapiens |
| IgG type | IgG1 |
| Reactivity | Human |
| Target | |
| Uniprot ID | Q9H7M9 |
| Description | Anti-B7-H5(onvatilimab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-B7-H5(onvatilimab biosimilar) mAb
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Product Data
图片
Figure 1. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human B7-H5 Protein, hFc Tag (PME101041) can bind Anti-B7-H5 Neutralizing antibody (BME100109) in a linear range of 2.44–625.00 ng/mL. In order to specifically detect BME100109, mouse anti-human Fab-specific antibody was used as detection antibody.
Figure 2. Flow cytometry analysis with 1 μg/mL Anti-B7-H5 (onvatilimab biosimilar) mAb (BME100109) on Expi293 cells transfected with Human B7-H5 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of anti-human B7-H5 mAb(BME100109).
(A) BME100109 does not bind to 293T cells that do not express B7-H5.
(B) A clear peak shift of BME100109 was seen compared to the control when incubated with B7-H5-expressing THP-1 cells, indicating strong binding of BME100109 to B7-H5. Antibodies were incubated at 5 μg/mL.
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