Common Name | MG-A271, MGA271 |
---|---|
Synonyms | B7-H3;CD276;B7 homolog 3 |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Host Species | Humanized |
IgG type | IgG1 |
Reactivity | Human |
Target | |
Uniprot ID | Q5ZPR3 |
Description | Anti-B7-H3 (enoblituzumab biosimilar) mAb |
Delivery | In Stock |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
Usage | Research use only |
Conjugate | Unconjugated |
Anti-B7-H3 (enoblituzumab biosimilar) mAb
Price: 50 μg ¥800.00 ; 100 μg ¥1500.00
Product Data
图片
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human B7-H3, mFc-His tagged protein PME100012 can bind Anti-B7-H3 Neutralizing antibody in a linear range of 0.24-31.25 ng/ml.
Figure 2. Flow cytometry analysis with 1μg/mL Anti-B7-H3 (enoblituzumab biosimilar) mAb (BME100010) on Hela cells (Blue histogram) or isotype control mAb on Hela cells (Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of anti-human B7-H3 mAb(BME100010).
(A) A clear peak shift of BME100010 was seen compared to the control when incubated with B7-H3-expressing Hela cells, indicating strong binding of BME100010 to B7-H3. Antibodies were incubated at 2 μg/mL.
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