Common Name | FPA-008,FPA008 |
---|---|
Synonyms | CSF1R;C-FMS;CD115;CSFR;FIM2;FMS;M-CSFR |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Host Species | Humanized |
IgG type | IgG4 |
Reactivity | Human |
Target | |
Uniprot ID | P07333 |
Description | Anti-CSF1R(cabiralizumab biosimilar) mAb |
Delivery | In Stock |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
Usage | Research use only |
Anti-CSF1R(cabiralizumab biosimilar) mAb
Price: 50 μg ¥800.00 ; 100 μg ¥1500.00
Product Data
图片
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human CSF1R , His tagged protein PME100067 can bind Anti-CSF1R Neutralizing antibody (BME100055) in a linear range of 0.2-16 ng/ml.
Figure 2. Flow cytometry analysis with Anti-CSF1R mAb 1 μg/ml (cabiralizumab) on Expi293 cells transfected with human CSF1R (Blue histogram)or Expi293 transfected with irrelevant protein(Red histogram) .
Figure 3. Flow cytometry analysis of antigen binding of anti-human CSF1R mAb(BME100055).
(A) A clear peak shift of BME100055 was seen compared to the control when incubated with CSF1R-expressing THP-1 cells, indicating strong binding of BME100055 to CSF1R. Antibodies were incubated at 2 μg/mL.
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