Anti-FOLR1 antibody(DMC391); IgG1 Chimeric mAb

Name: Anti-FOLR1 antibody(DMC391); IgG1 Chimeric mAb - 专注肿瘤免疫
SKU: DMC100391
Price: 438.00 CNY
Availability: InStock

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

SKU: DMC100391 Category: Monoclonal Antibodies

Datasheet

MSDS

Product Data

Clone ID	DMC391
Target	FOLR1
Synonyms	FBP; FOLR; FRalpha
Host Species	Rabbit
Description	Anti-FOLR1 antibody(DMC391); IgG1 Chimeric mAb
Delivery	In Stock
Uniprot ID	P15328
IgG type	Rabbit/Human Fc chimeric IgG1
Clonality	Monoclonal
Reactivity	Human
Applications	Flow Cyt
Recommended Dilutions	Flow Cyt 1:100
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives; and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters; multiple transcription start sites; and alternative splicing; multiple transcript variants encoding the same protein have been found for this gene.
Usage	Research use only
Conjugate	Unconjugated

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Figure 1. FOLR1 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-FOLR1 (DMC391) on Expi293 cells transfected with human FOLR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).

Figure 2. Flow cytometry analysis of antigen binding of anti-human FOLR1 mAb(DMC100391).
(A) DMC100391 does weakly bind to Jurkat cells that do not express FOLR1.
(B) A clear peak shift of DMC100391 was seen compared to the control when incubated with FOLR1-expressing Hela cells, indicating strong binding of DMC100391 to FOLR1. Antibodies were incubated at 2 μg/mL.

Anti-FOLR1 antibody(DMC391); IgG1 Chimeric mAb

Product Data

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