Human B7-H4 Protein, hFc Tag

Name: Human B7-H4 Protein, hFc Tag - 专注肿瘤免疫
SKU: PME100053
Price: 3999.00 CNY
Availability: InStock

Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00

SKU: PME100053 Category: ECD Proteins

Datasheet

MSDS

Product Data

Target	B7-H4
Synonyms	B7-H4;B7h.5;B7H4;B7S1;B7X;PRO1291;VCTN1
Description	Recombinant Human B7-H4 protein with C-terminal human Fc
Delivery	In Stock
Uniprot ID	Q7Z7D3
Expression Host	HEK293
Tag	C-Human Fc Tag
Molecular Characterization	B7-H4 (Phe29-Ala258) hFc(Glu99-Ala330)
Molecular Weight	The protein has a predicted molecular mass of 51.4 kDa after removal of the signal peptide.The apparent molecular mass of B7-H4-hFc is approximately 100-130 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
Usage	Research use only
Conjugate	Unconjugated

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Figure 1. Human B7-H4 Protein, hFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human B7-H4, hFc-His tagged protein (PME100053) can bind Anti-B7-H4 Neutralizing antibody (BME100078) in a linear range of 3.2-80 ng/ml.
PME100053-B7-H4-Fig.3-Elisa-2.jpg
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human B7-H4 Protein, hFc Tag (PME100053) can bind Anti-B7-H4(AZD-8205 biosimilar) mAb (BME100190) in a linear range of 3.20–80 ng/mL.
PME100053-B7-H4-Fig.4-Elisa-3.jpg
Figure 4. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human B7-H4 Protein, hFc Tag (PME100053) can bind Anti-B7-H4(XMT-1660 biosimilar) mAb (BME100192) in a linear range of 3.20–80 ng/mL.

Human B7-H4 Protein, hFc Tag

Product Data

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