Target | |
---|---|
Synonyms | Beta-Nerve Growth Factor;Beta-NGF;NGF;NGFB;-NGF |
Description | Recombinant Human Beta-Nerve Growth Factor is produced by our Mammalian expression system and the target gene encoding Ser122-Arg239 is expressed. |
Delivery | In Stock |
Uniprot ID | P01138 |
Expression Host | HEK293 |
Tag | |
Molecular Characterization | Not available |
Molecular Weight | 13.3 KDa |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.0. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits a, β, and γ; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity. |
Usage | Research use only |
Human Beta-NGF (Mammalian) Protein
Price: 10 μg ¥240.00 ; 50 μg ¥720.00
Product Data
图片
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
相关产品
ECD Proteins
SKU: PME100017 Target: CTLA-4
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100016 Target: CD48
Price: 10μg ¥854.00 ; 50μg ¥3133.00 ; 100 μg ¥4699.00
ECD Proteins
SKU: PME100072 Target: ACE2
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100012 Target: B7-H3
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100019 Target: GITR
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100018 Target: GITR
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100036 Target: S protein RBD
Price: 10μg ¥818.00 ; 50μg ¥2999.00 ; 100 μg ¥4499.00
ECD Proteins
SKU: PME100670 Target: CD166
Price: 10μg ¥636.00 ; 50μg ¥2333.00 ; 100 μg ¥3499.00
ECD Proteins
SKU: PME100007 Target: FLT3
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100025 Target: PD-1
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100671 Target: RSPO3
Price: 10μg ¥673.00 ; 50μg ¥2466.00 ; 100 μg ¥3699.00
ECD Proteins
SKU: PME100649 Target: KRAS
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00