Target | |
---|---|
Synonyms | Interleukin-15;IL-15;IL15 |
Description | Recombinant Human Interleukin-15 is produced by our E.coli expression system and the target gene encoding Asn49-Ser162 is expressed. |
Delivery | In Stock |
Uniprot ID | P40933 |
Expression Host | E.coli |
Tag | |
Molecular Characterization | Not available |
Molecular Weight | 12.5 KDa |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8 memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15. |
Usage | Research use only |
Human IL-15 Protein
Price: 10 μg ¥1200.00 ; 50 μg ¥3520.00
Product Data
图片
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
Figure 2. Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 40-200pg/ml.
相关产品
ECD Proteins
SKU: PME100009 Target: SIRPa
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100655 Target: FOLR2
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100μg ¥4299.00
ECD Proteins
SKU: PME100667 Target: GFAP
Price: 10μg ¥673.00 ; 50μg ¥2466.00 ; 100 μg ¥3699.00
ECD Proteins
SKU: PME100008 Target: CD47
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100006 Target: CD138
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100021 Target: OX40 Ligand
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100017 Target: CTLA-4
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100003 Target: CD123
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100670 Target: CD166
Price: 10μg ¥636.00 ; 50μg ¥2333.00 ; 100 μg ¥3499.00
ECD Proteins
SKU: PME100036 Target: S protein RBD
Price: 10μg ¥818.00 ; 50μg ¥2999.00 ; 100 μg ¥4499.00
ECD Proteins
SKU: PME100005 Target: CD22
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100018 Target: GITR
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00