Target | |
---|---|
Synonyms | U-PAR;uPAR;CD87 |
Description | Recombinant human PLAUR protein with C-terminal 6×His tag |
Delivery | In Stock |
Uniprot ID | Q03405 |
Expression Host | HEK293 |
Tag | C-6×His Tag |
Molecular Characterization | PLAUR(Leu23-Arg303) 6×His tag |
Molecular Weight | The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of PLAUR-His is approximately 35-55 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] |
Usage | Research use only |
Human PLAUR Protein, His Tag
Price: 10μg ¥727.00 ; 50μg ¥2700.00 ; 100 μg ¥3999.00
Product Data
图片
Figure 1. Human PLAUR Protein, His Tag on SDS-PAGE under reducing condition.
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