| Clone ID | DM178 |
|---|---|
| Target | |
| Synonyms | TIGIT;VSIG9;VSTM3 |
| Host Species | Rabbit |
| Description | Anti-TIGIT antibody(DM178); Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | Q495A1 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-TIGIT antibody(DM178); Rabbit mAb
Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00
Product Data
图片
Figure 1. Flow cytometry analysis with Anti-TIGIT (DM178) on Expi293 cells transfected with human TIGIT (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Competition assay demonstrating DM178 blockade of CD155 binding to Jurkat cell line transfected with human TIGIT,and competitive activity is better than etigilimab biosimilar.
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