Clone ID | DMC283 |
---|---|
Target | |
Synonyms | PSGL-1;PSGL1;CD162;SELPLG;Selectin P ligand |
Host Species | Rabbit |
Description | PE-conjugated Anti-CD162 antibody(DMC283); IgG1 Chimeric mAb |
Delivery | 3-4 weeks |
Uniprot ID | Q14242 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-; E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such; this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications; tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans; for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-CD162 antibody(DMC283); IgG1 Chimeric mAb
Price: 100 test ¥3880.00
Product Data
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