| Tag | C-Flag&Strep Tag |
|---|---|
| Target | |
| Synonyms | ADRB1R; B1AR; BETA1AR; FNSS2; RHR |
| Description | Human ADRB1-Strep full length protein-synthetic nanodisc |
| Delivery | 6~8weeks |
| Uniprot ID | P08588 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Dilated cardiomyopathy, Endocytosis, Gap junction, Neuroactive ligand-receptor interaction |
| Molecular Weight | The human full length ADRB1-Strep protein has a MW of 51.2 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human ADRB1-Strep full length protein-synthetic nanodisc
Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00
Product Data
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