Name: Human PTGDR2-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120125

Tag	C-Flag&Strep Tag
Target	PTGDR2
Synonyms	CD294; CRTH2; DL1R; DP2; GPR44
Description	Human PTGDR2-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9Y5Y4
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length PTGDR2-Strep protein has a MW of 43.3 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a G-protein-coupled receptor that is preferentially expressed in CD4 effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
Usage	Research use only
Conjugate	Unconjugated

Human PTGDR2-Strep full length protein-synthetic nanodisc