| Target | |
|---|---|
| Synonyms | T4; IMD79; Leu-3; OKT4D; CD4mut |
| Description | Biotinylated Human CD4 full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | P01730 |
| Expression Host | HEK293 |
| Protein Families | Transmembrane |
| Protein Pathways | Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway |
| Molecular Weight | The human full length CD4 Protein has a MW of 55.9 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020] |
| Usage | Research use only |
Biotinylated Human CD4 full length protein-synthetic nanodisc
Price: 10 μg ￥6930.00 ; 50 μg ￥33000.00 ; 100 μg ￥60500.00
Product Data
图片
Figure 1. ELISA plate pre-coated by 0.2 μg/mL (100 μL/well) Anti-Flag monoclonal antibody can bind Biotinylated Human CD4 full length protein-synthetic nanodisc (FLP100160B) in a linear range of 16–2000 ng/mL. In order to specifically detect FLP100160B, HRP Conjugated Streptavidin was used as detection antibody.
Figure 2. Biotinylated Human CD4-Nanodisc, Flag Tag on SDS-PAGE
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