Name: Human HCN4 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100754

Tag	C-Flag Tag
Target	HCN4
Synonyms	SSS2
Description	Human HCN4 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9Y3Q4
Expression Host	HEK293
Protein Families	Ion Channels: Cyclic nucleotide gated
Protein Pathways	N/A
Molecular Weight	The human full length HCN4 protein has a MW of 129kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]
Usage	Research use only
Conjugate	Unconjugated

Human HCN4 full length protein-synthetic nanodisc