Name: Biotinylated Anti-SN38 antibody(1G1); Rabbit mAb - 专注肿瘤免疫
SKU: DME101020B

Clone ID	1G1
Target	SN38
Synonyms	N.A.
Host Species	Rabbit
Description	Biotinylated Anti-SN38 antibody(1G1); Rabbit mAb
Delivery	2-3 weeks
Uniprot ID	N.A.
IgG type	Rabbit IgG
Clonality	Monoclonal
Reactivity	N.A.
Applications	ELISA
Recommended Dilutions	ELISA 1:5000-10000
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	SN38, a potent chemotherapeutic derived from irinotecan, plays a pivotal role in colorectal cancer treatment. As the active form of irinotecan, SN38 operates as an effective DNA topoisomerase I inhibitor, inducing cell death in cancer cells. Notably, SN38's potential is harnessed in Antibody-Drug Conjugates (ADCs), where it is delivered to tumor sites through innovative methods like liposomes and nanoparticles. This targeted approach enhances SN38's efficacy, emphasizing its crucial role in ADC-based strategies for precise and potent colorectal cancer therapy.
Usage	Research use only
Conjugate	Biotinylated

Biotinylated Anti-SN38 antibody(1G1); Rabbit mAb