Target | |
---|---|
Synonyms | KOR-3, KOR3, NOCIR, NOP, NOPr, OOR, OPRL, ORL1, PNOCR |
Description | Human OPRX full length protein-synthetic nanodisc |
Delivery | 6~8weeks |
Uniprot ID | P41146 |
Expression Host | HEK293 |
Protein Families | GPCR,Transmembrane,Druggable Genome, |
Protein Pathways | GPCRDB Class A Rhodopsin-like,Peptide GPCRs, |
Molecular Weight | The human full length OPRX protein has a MW of 40.7kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017] |
Usage | Research use only |
![Awaiting product image](https://www.dimabio.cn/wp-content/uploads/woocommerce-placeholder-400x400.png)
Human OPRX full length protein-synthetic nanodisc
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
Product Data
图片
相关产品
Full Length Transmembrane Proteins
SKU: FLP100010 Target: GPRC5D
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Full Length Transmembrane Proteins
SKU: FLP100004 Target: CLDN6
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Full Length Transmembrane Proteins
SKU: FLP100030 Target: CD63
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
Full Length Transmembrane Proteins
SKU: FLP100034 Target: CD63
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Full Length Transmembrane Proteins
SKU: FLP100020 Target: ADORA2A
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
Full Length Transmembrane Proteins
SKU: FLP100001 Target: CCR8
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Full Length Transmembrane Proteins
SKU: FLP100006 Target: CLDN18.2
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Full Length Transmembrane Proteins
SKU: FLP100012 Target: SSTR2
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Full Length Transmembrane Proteins
SKU: FLP100008 Target: CLDN6
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
Full Length Transmembrane Proteins
SKU: FLP100026 Target: CD20
Price: 50 μg ¥8000.00 ; 100 μg ¥10800.00
Full Length Transmembrane Proteins
SKU: FLP100032 Target: SLC25A4
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
Full Length Transmembrane Proteins
SKU: FLP100033 Target: TRPA1
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00