Name: Human MC3R full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100345

Tag	C-Flag Tag
Target	MC3R
Synonyms	BMIQ9, MC3, MC3-R, OB20, OQTL
Description	Human MC3R full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P41968
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,Peptide GPCRs,Metabolic and Obesity,
Molecular Weight	The human full length MC3R protein has a MW of 36kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human MC3R full length protein-synthetic nanodisc