Target | |
---|---|
Synonyms | BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9 |
Description | Human LT4R2 full length protein-synthetic nanodisc |
Delivery | 6~8weeks |
Uniprot ID | Q9NPC1 |
Expression Host | HEK293 |
Protein Families | GPCR,Transmembrane,Druggable Genome, |
Protein Pathways | GPCRDB Other,Asthma,Autoimmune & Inflammatory Response, |
Molecular Weight | The human full length LT4R2 protein has a MW of 37.9kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.[UniProtKB/Swiss-Prot Function] |
Usage | Research use only |
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Human LT4R2 full length protein-synthetic nanodisc
Price: 10 μg ¥6300.00 ;50 μg ¥30000.00 ; 100 μg ¥55000.00
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