Name: Human CRHR1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100228

Tag	C-Flag Tag
Target	CRHR1
Synonyms	CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRHR, CRHR1L
Description	Human CRHR1 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	B3TIK8
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class B Secretin-like,Smooth muscle contraction,Cancer,Neurotrophin & Receptors,
Molecular Weight	The human full length CRHR1 protein has a MW of 36.6kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016]
Usage	Research use only
Conjugate	Unconjugated

Human CRHR1 full length protein-synthetic nanodisc

Product Data

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Human CRHR1 full length protein-synthetic nanodisc

Product Data

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