Name: Human BKRB1 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100213

Tag	C-Flag Tag
Target	BKRB1
Synonyms	B1BKR, B1R, BKB1R, BKR1, BRADYB1
Description	Human BKRB1 full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P46663
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,Peptide GPCRs,Regulation of Actin Cytoskeleton KEGG,Cancer,
Molecular Weight	The human full length BKRB1 protein has a MW of 40.5kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq, Aug 2020]
Usage	Research use only
Conjugate	Unconjugated

Human BKRB1 full length protein-synthetic nanodisc

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Human BKRB1 full length protein-synthetic nanodisc

Product Data

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