Target | |
---|---|
Synonyms | ARH6;ARHB;MST081;MSTP081;RHOH6 |
Description | Recombinant Human RHOB Protein with C-terminal human Fc tag |
Delivery | In Stock |
Uniprot ID | P62745 |
Expression Host | HEK293 |
Tag | C-Human Fc Tag |
Molecular Characterization | RHOB(Met1-Gly188) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 47.4 kDa after removal of the signal peptide. The apparent molecular mass of RHOB-hFc is approximately 35-55 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.[UniProtKB/Swiss-Prot Function] |
Usage | Research use only |
Conjugate | Unconjugated |
Human RHOB Protein, hFc Tag
Price: 10μg ¥690.00 ; 50μg ¥2500.00 ; 100μg ¥3699.00
Product Data
图片
Figure 1.Human RHOB Protein, hFc Tag on SDS-PAGE under reducing condition.
相关产品
ECD Proteins
SKU: PME100006 Target: CD138
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100667 Target: GFAP
Price: 10μg ¥673.00 ; 50μg ¥2466.00 ; 100 μg ¥3699.00
ECD Proteins
SKU: PME100002 Target: CS1
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100012 Target: B7-H3
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100648 Target: NEFL
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100649 Target: KRAS
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100011 Target: 4-1BB
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
ECD Proteins
SKU: PME100019 Target: GITR
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100008 Target: CD47
Price: 10μg ¥782.00 ; 50μg ¥2866.00 ; 100 μg ¥4299.00
ECD Proteins
SKU: PME100003 Target: CD123
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100004 Target: CD38
Price: 10μg ¥727.00 ; 50μg ¥2666.00 ; 100 μg ¥3999.00
ECD Proteins
SKU: PME100017 Target: CTLA-4
Price: 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00