Name: Human MRGRD full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100349

Tag	C-Flag Tag
Target	MRGRD
Synonyms	MRGD, TGR7
Description	Human MRGRD full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q8TDS7
Expression Host	HEK293
Protein Families	Transmembrane,Druggable Genome,
Protein Pathways	N/A
Molecular Weight	The human full length MRGRD protein has a MW of 36.1kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human MRGRD full length protein-synthetic nanodisc