Name: Human ADGRG1-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120104

Tag	C-Flag&Strep Tag
Target	ADGRG1
Synonyms	BFPP; BPPR; GPR56; TM7LN4; TM7XN1
Description	Human ADGRG1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9Y653
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	N.A.
Molecular Weight	The human full length ADGRG1-Strep protein has a MW of 77.7 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	A member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria.
Usage	Research use only
Conjugate	Unconjugated

Human ADGRG1-Strep full length protein-synthetic nanodisc