Name: Human XCR1-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120120

Tag	C-Flag&Strep Tag
Target	XCR1
Synonyms	CCXCR1; GPR5
Description	Human XCR1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P46094
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Molecular Weight	The human full length XCR1-Strep protein has a MW of 38.5 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.
Usage	Research use only
Conjugate	Unconjugated

Human XCR1-Strep full length protein-synthetic nanodisc

Product Data

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Human XCR1-Strep full length protein-synthetic nanodisc

Product Data

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