| Target | |
|---|---|
| Synonyms | SCYA11 |
| Description | Recombinant Human CCL11 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P51671 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | CCL11(Thr30-Pro97) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 34.0 kDa after removal of the signal peptide. The apparent molecular mass of CCL11-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CCL11 Protein, hFc Tag
Price: 10μg ￥636.00 ; 50μg ￥2333.00 ; 100μg ￥3499.00
Product Data
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Figure 1.Human CCL11 Protein, hFc Tag on SDS-PAGE under reducing condition.
