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Human GITR Ligand Protein, His tag

产品概述
Catalog Number PME100478
Package 10μg ¥909.00 ; 50μg ¥3333.00 ; 100 μg ¥4999.00
Description Recombinant human GITR Ligand protein with C-terminal His tag
Synonyms TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Delivery In Stock
Uniprot ID Q9UNG2
Expression Host HEK293
Tag C-His tag
Molecular Characterization 这里上传图片
Molecular Weight The protein has a predicted molecular mass of 15.3 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
Usage Research use only
Images

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Figure 1. Human GITR Ligand Protein, His Tag on SDS-PAGE under reducing condition.

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Figure 2.  Flow cytometry analysis with 1 μg/mL Human GITR Ligand Protein, His tag (PME100478) on Expi293 cells transfected with human GITR (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Background The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
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