Human Claudin-6 full length protein -MNP
| Catalog Number | FLP100004 |
|---|---|
| package | 50 μg ￥8000.00 ; 100 μg ￥10800.00 |
| Description | Human Claudin-6 full length membrane nanoparticles (MNPs) |
| Expression Host | HEK293 |
| Symbol | CLDN6 |
| ORF Size | 660bp |
| Formulation | Supplied in 1xPBS (pH 7.4) |
| Storage | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
| ACCN | NM_021195 |
| Protein Families | Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| MW | The human full length Claudin-6 Protein has a MW of 23 kDa |
| Protein Summary | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
| UniProt ID | P56747 |
| Delivery | In Stock |
| Images |
Figure 1. ELISA plates were pre-coated with 0.5 μg/per well purified human Claudin6 MNPs. Serial diluted Anti-Claudin6 monoclonal antibody (BME100082) solutions were added, washed, and incubated with secondary antibody before ELISA reading. From above data, the EC50 for BME100082 binding with Claudin6 MNPs is 34.36 ng/ml.
Figure 2. FACS analysis Claudin6 membrane nanoparticle |
| 说明书 | 立即下载 | COA | 立即下载 |
|---|---|---|---|
| MSDS | 立即下载 | ||
简体中文
English
