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Human CD63 full length protein-MNP
Catalog Number | FLP100034 |
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package | 50 μg ¥8000.00 ; 100 μg ¥10800.00 |
Description | Human CD63 full length protein membrane nanoparticles (MNPs) |
Expression Host | HEK293 |
Symbol | CD63 |
ORF Size | 714 bp |
Formulation | Supplied in 1xPBS (pH 7.4) |
Storage | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
ACCN | NM_001780 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Lysosome |
MW | The human full length CD63 protein has a MW of 25.6 kDa |
Protein Summary | The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
UniProt ID | P08962 |
Delivery | In Stock |
Images |
Figure1. Elisa plates were pre-coated with 0.5μg/per well purified human CD63 full length membrane nanoparticles. Serial diluted anti-CD63 monoclonal antibody (DMC100425) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CD63 monoclonal antibody binding with CD63 full length membrane nanoparticles is 61.65ng/ml.
Figure2. FACS analysis of CD63 MNPs |
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