| Target | |
|---|---|
| Synonyms | ACE-2;ACEH;ACE2  | 
		
| Description | Recombinant human ACE2 protein with C-terminal mouse Fc tag  | 
		
| Delivery | In Stock  | 
		
| Uniprot ID | Q9BYF1  | 
		
| Expression Host | HEK293  | 
		
| Tag | C-Mouse Fc Tag  | 
		
| Molecular Characterization | ACE2(Gln18-Ser740) mFc(Pro99-Lys330)  | 
		
| Molecular Weight | The protein has a predicted molecular mass of 109.7 kDa after removal of the signal peptide.  | 
		
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.  | 
		
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.  | 
		
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.  | 
		
| Background | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.  | 
		
| Usage | Research use only  | 
		
| Conjugate | Unconjugated  | 
		
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