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18062749453
Anti-TNFSF15 antibody(DMC464), IgG1 Chimeric mAb
| Clone ID |
DMC464 |
|---|---|
| Immunogen |
Recombinant human TNFSF15 (Leu72-Leu251) ( PME100752) produced by using human HEK293 cells |
| Buffer | 1XPBS |
| Catalog Number | DMC100464 |
|---|---|
| Package | 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00 |
| Delivery | In Stock |
| Synonyms | TL1, VEGI |
| Host Species | Rabbit |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Formulation | Liquid |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1/100 |
| Storage | Store at -20°C for 12 months (Avoid repeated freezing and thawing) |
| Usage | Research use only |
| Images |
Figure 1. Flow cytometry analysis with Anti-TNFSF15 (DMC464) on Expi293 cells transfected with human TNFSF15 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |
| 说明书 | 立即下载 | COA | 立即下载 |
|---|---|---|---|
| MSDS | 立即下载 | ||
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