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Anti-CXCR1 antibody(DMC470), IgG1 Chimeric mAb
Clone ID |
DMC470 |
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Immunogen |
Recombinant human CXCR1(Met1-Lys39) (PME100820) produced by using human HEK293 cells |
Buffer | 1XPBS |
Catalog Number | DMC100470 |
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Package | 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00 |
Delivery | In Stock |
Synonyms | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA |
Host Species | Rabbit |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Formulation | Liquid |
Purification | Purified from cell culture supernatant by affinity chromatography |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1/100 |
Storage | Store at -20°C for 12 months (Avoid repeated freezing and thawing) |
Usage | Research use only |
Images |
Figure 1. Flow cytometry analysis with Anti-CXCR1 (DMC470) on Expi293 cells transfected with human CXCR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
Background | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] |
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