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Anti-CXCR1 antibody(DMC470), IgG1 Chimeric mAb

产品概述
Clone ID DMC470
Immunogen Recombinant human CXCR1(Met1-Lys39) (PME100820) produced by using human HEK293 cells
Buffer 1XPBS
Catalog Number DMC100470
Package 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Delivery In Stock
Synonyms C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
Host Species Rabbit
IgG type Rabbit/Human Fc chimeric IgG1
Clonality Monoclonal
Formulation Liquid
Purification Purified from cell culture supernatant by affinity chromatography
Reactivity Human
Applications Flow Cyt
Recommended Dilutions Flow Cyt 1/100
Storage Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Usage Research use only
Images

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Figure 1. Flow cytometry analysis with Anti-CXCR1 (DMC470) on Expi293 cells transfected with human CXCR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Background The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]
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